Ubuhlungu bomlenze ongasekho (PLP) buyisimo esiyinselele futhi esivame ukukhubaza esibhekwa ngabantu abaningi abasuke belulwe umlenze. Lolu hlobo lobuhlungu be-neuropathic lubonakala ngokuzwa ukuthi umlenze ongasekho usakhona futhi uvame ukubuhlungu. Izindlela zokwelapha ezijwayelekile ziye zaba nempumelelo encane ekunikezeni impumuzo ehlala njalo. Kodwa-ke, intuthuko yakamuva ibonise ukuthi i-Botox (i-botulinum toxin) ingaba yindlela ephumelelayo yokuphatha lesi simo sobuhlungu esiyinkimbinkimbi. I-Botox, eyaziwa kakhulu ngokusebenzisa kwayo kwezobuhle njengokwelula imibimbi yamehlo nemigqa yebunzi, ibonise imiphumela ephumelelayo yokwelapha ngaphezu kokubukeka, ikakhulukazi ekulawuleni ubuhlungu bezinzwa.

Ucwaningo oluyimpumelelo olwenziwe e-Ukraine luhlolisise ukusebenza kwe-Botox ekunciphiseni ubuhlungu bezitho ezingekho phakathi kwabantu abasusiwe. Abacwaningi bahlose ukukala izinga lokuncishiswa kobuhlungu nokuhlola izinzuzo zesikhathi eside zemijovo ye-Botox kulolu hlobo lweziguli. Ucwaningo lwase-Ukraine lubalulekile ekwandiseni ukuqonda ukuthi i-neurotoxin etholakala ku-Clostridium botulinum ingasetshenziswa kanjani ekulawuleni ubuhlungu be-neuropathic. Ngokuhlanganisa iziphetho zemizwa kanye nokuvuvukala kwemisipha, i-Botox inganciphisa imiyalezo engajwayelekile yemithambo yemisipha ebangela imizwa yezitho ezingekho.

Ubuhlungu bomlenze ongasekho buthinta cishe u-50% kuya ku-80% wabantu ngemuva kokunqunywa umlenze, okuthinta kakhulu ikhwalithi yokuphila. Imithi ejwayelekile yokudambisa ubuhlungu ivame ukungasebenzi kahle, okuholela ekufuneni izindlela zokwelapha ezihlukile. Ucwaningo lwase-Ukraine lwembule ukuthi iziguli ezathola imijovo ye-Botox zabika ukwehla okukhulu kobukhulu nobuningi bobuhlungu uma kuqhathaniswa namaqembu alawulayo. Lezi zibalo zigcizelela amandla e-Botox njengendlela ewusizo ekwelapheni ubuhlungu kwabantu abanqanywe imilenze. Okubalulekile ukuthi le ndlela yokwelapha ibuye yabonisa ukuncipha kobuhlungu obuhlobene nemisipha obuvame ukuhambisana nobuhlungu bezinzwa, okunikeza inzuzo ephindwe kabili.

Ucwaningo lusebenzise indlela eqinile yokuhlola ubuhlungu, ehlanganisa izikali zobuhlungu ezithinta umuntu ngamunye nokuhlolwa kwezinzwa okubonakalayo. Iziguli zaqashwa izinyanga eziningana ukuze kuhlale kuhlanganiswa imiphumela esheshayo nehlala njalo yokwelashwa nge-Botox. Okutholakele okubalulekile kufaka phakathi ukuncipha okukhulu kwezikali zobuhlungu nokuthuthuka kwamakhono okusebenza kweziguli. Le ndlela ephelele yavumela abacwaningi ukuthi baqinisekise ukusebenza kwe-Botox ngenkathi beqinisekisa ukuphepha nokubekezelelana. Le ndlela iphinde yagqamisa ukubaluleka kwezindlela zokujova ezenzelwe umuntu ngamunye ezihambisana nezindlela ezithile zobuhlungu zesiguli ngasinye.

Amasu ahlakaniphile okujova athuthukiswe ngesikhathi sokufunda alungise ukulethwa kwe-Botox ezindaweni ezithintekayo zemizwa, athuthukisa imiphumela yokwelapha. Ngokungafani nezindlela zokwelapha ezijwayelekile, lezi zindlela zigxila ekubekeni ngokunembayo lapho kujovwa khona ukuze kuthinteke ukusebenza ngokweqile kwemizwa ngaphandle kokubangela ukukhubazeka kwemisipha. Imiphumela yesikhathi eside eboniwe ihlanganisa ukudambisa okuhlala njalo kobuhlungu okuhlala izinyanga eziningana ngemuva kokwelashwa, ngokufakwa kabusha okugcina ukusebenza kahle. Le nqubekela phambili ivula izindlela ezintsha zokuphatha hhayi ubuhlungu bomlenze ongasekho kuphela kodwa nezinye izinhlobo zezinkinga ezihlobene nemizwa. Impumelelo yalezi zindlela igcizelela indawo eguqukayo yokusetshenziswa kwe-Botox ekwelashweni kwezokwelapha.

Ngaphandle kobuhlungu bemithambo eyinyonyo, i-Botox ibonisa ithemba ekubhekaneni nezinhlobonhlobo zezimo ezibuhlungu zemithambo. Indlela yayo yokusebenza, ehlanganisa ukuvimela ukukhishwa kwe-neurotransmitter nokuphumula kwemisipha, iyenza ibe yinto eguquguqukayo ekulawuleni ubuhlungu. Ucwaningo lwase-Ukraine lunikela ngobufakazi obandayo obusekela ukusetshenziswa kwe-Botox ezindaweni zezokwelapha kubuhlungu obungapheli bemithambo. Lokhu kunemiphumela ebalulekile ezigulini ezihlupheka ngezimo ezifana ne-post-herpetic neuralgia, i-diabetic neuropathy, kanye ne-complex regional pain syndrome. Ngokwandisa ububanzi bokwelapha be-Botox, odokotela bangahlinzeka ngamasu aphelele kakhulu okuphatha ubuhlungu.

UDkt. Steven Cohen, uchwepheshe ohamba phambili ekuphathweni kobuhlungu, ube nendima enkulu ekuthuthukiseni ucwaningo ngendima ye-Botox ekudambiseni ubuhlungu obubangelwa imithambo. Imibono yakhe ngemithetho yomjovo nezinkambiso zokukhetha iziguli ziye zathuthukisa izindlela zokwelapha, kwathuthukisa imiphumela yokwelashwa. Ucwaningo oluzayo, olukhuthazwe yimiphumela efana naleyo evela e-Ukraine, luhlose ukuhlola izikhathi ezifanele zokudosa, izindlela zokudambisa ubuhlungu, kanye nokwelashwa okuhlanganisiwe. Le mizamo izoqhubeka nokuqinisekisa i-Botox njengokwelashwa okubalulekile kwezifo ezihlukahlukene zobuhlungu, okungase kuguqule izindlela zokunakekelwa kweziguli.

Isizathu sokuhlola i-Botox yobuhlungu bezitho ezingekho siveliswa isidingo esiphuthumayo sokuthuthukisa ikhwalithi yokuphila kwabantu abanqanyuliwe izitho, abavame ukubhekana nobuhlungu obungapheli, obuvimbela ukwelashwa. Abacwaningi baholwa ukuzinikela ekutholeni izindlela zokwelapha ezisebenzayo ezibhekana nezidingo zezokwelapha ezinganakekelwa. Ukuxhaswa kwezimali kulezi zifundo kuvame ukuvela ezinkampanini zobuchwepheshe bezokwelapha ezitshale ezithuthukisweni zokwelapha, okubandakanya iDermax, inkampani eyaziwa ngezixazululo zayo ezintsha zezokwelapha. IDermax isekela ucwaningo oluhlanganisa izicelo zobuhle nezokwelapha ze-botulinum toxin, igqamisa umkhawulo wayo wokuncintisana nokuzinikela ekuthuthukiseni imiphumela yeziguli.

Ngokuphetha, i-Botox yindlela yokuguqula ukuphatha ubuhlungu be-phantom limb, enikeza ithemba eziningi iziguli ezihlupheka kulesi simo esiyinselele. Ucwaningo lwase-Ukraine, oluhlanganiswe nezinye izindlela ezintsha, luqinisekisa ukusebenza nokuphepha kwe-Botox njengokwelashwa kobuhlungu be-neuropathic. Ezintathelini kanye nochwepheshe bezempilo abafuna ulwazi olwengeziwe, izinsiza ziyatholakala ngokusebenzisa izincwadi zocwaningo lwezokwelapha namakhasi enkampani anikezelwe njengalawa:Mayelana NathikanyeIzindabakusuka kwaDermax. Lezi zinkundla zinikeza imininingwane ngentuthuko eqhubekayo nendima yenkampani ekusunguleni izicelo zeBotox.

Ngemininingwane eningiliziwe yomkhiqizo nokusekelwa okuhlobene neBotox nezinye ubuchwepheshe bezokwelapha, sicela uvakashele i-Imikhiqizo kanye Ukusekelwa amakhasi, uqinisekisa ukufinyelela okuphelele ezixazululweni ezintsha ezithuthukisa imiphumela yokwelapha.